Penile Curvature/Peyronie's Disease
Peyronie’s disease is characterized by an abnormal curvature of the penis when erect, and may cause erectile dysfunction. Peyronie’s disease affects men of all ages, and is caused by scar tissue in the erectile tissue that prevents straightening of the penis with erection.
Congenital penile curvature, is a malformation that occurs during an early stage of development. It might not be noticed until puberty when erections become more common.
Treatments for Peyronie’s Disease/congenital penile curvature
While controlled studies have not shown clear benefit, there have been scattered reports that pentoxiphylline, vitamin E, potassium aminobenzoate (potaba), colchicine, and others may help.
Mild to moderate cases of Peyronie's disease can sometimes be effectively treated with penile injection of new plaque dissolving drug Xiaflex (collagenase clostridium histolyticum). This requires examination and precertification through insurance carrier.
Verapamil can reduce fibrous tissue and ease pain. They may also be delivered by injection directly into the plaque.
When Peyronie’s Disease/ congenital penile curvature cause a severely curved penis with pain or sexual dysfunction surgery is an option. The options are to lengthen the shortened side of the penis, or in less severe cases to shorten the opposite unaffected side of the penis. These procedures may be combined with a penile prosthesis implant when there is associated erectile dysfunction.